- Failed to initialize the physics system.
- Please ensure you have an updated version of the PhysX System Software installed.
- Failed to initialize the physics system. Please ensure you have an updated version of the PhysX System Software installed.
If you don't have PhysX, then install it!
If you do have PhysX and some other game which uses this runs just fine then the following fix will work for you. First make sure that you have PhysX installed, to do this click on Start Menu and then type "Programs and Features", scroll down and see if PhysX is present there. If it is, then it means you have PhysX installed, if it isn't there then you have to install it.
If you have PhysX listed in it then do the following to fix the issue with ME2.
Go to Control Panel (open up Start Menu, type in 'Control Panel' and click on the one that pops up)
Go into Programs in the control panel (you can also reach this directly from start menu by typing "Programs and Features" in the start menu)
If you clicked on 'Programs' then click on 'Programs and Features'
Scroll down, find PhysX and then right click on it. In the context menu, select 'Repair'.
Reboot your machine and it all should be fixed.